Natural human Angiostatin protein (ab88558)

Overview

Description

  • NatureNatural
  • SourceNative
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab88558 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityab88558 demonstrates an antiproliferative effect when tested in a growth factor-induced endothelial cell proliferation assay.
  • Applications

    SDS-PAGE

    Functional Studies

  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Additional notesab88558 demonstrates an antiproliferative effect when tested in a growth factor-induced endothelial cell proliferation assay.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.15M Sodium chloride, 20mM HEPES, pH 7.4

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • RelevanceAngiostatin is an internal proteolytic fragment of plasminogen, containing at least three Kringle domains. The Kringle domains have specific anti-migratory and anti-proliferative activities. Angiostatin, an endogenous angiogenesis inhibitor, inhibits endothelial cell proliferation in vitro and angiogenesis in vivo. It is a potent and specific natural inhibitor of angiogenisis and metastatic tumor growth.
  • Cellular localizationSecreted

Natural human Angiostatin protein images

  • 4-12% SDS-PAGE analysis of Reduced and Non-reduced samples of ab88558 (1µg).
    Molecular weight markers: Myosin (191 kDa), Phosphorylase B (97 kDa), BSA (64 kDa), Glutamic Dehydrogenase (51 kDa), Alcohol Dehydrogenase (39 kDa), Carbonic Anhydrase (28 kDa), Myoglobin Red (19 kDa), Lysozyme (14 kDa)

References for Natural human Angiostatin protein (ab88558)

ab88558 has not yet been referenced specifically in any publications.

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