Overview

Description

  • NatureNatural
  • SourceNative
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab90925 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.

  • FormLyophilised
  • Additional notesPrepared from fresh, non-frozen plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Preservative: None
    Constituents: 10mM Ammonium bicarbonate, pH 7.4

  • ReconstitutionAfter initial centrifugation, we suggest the addition of the lyophilization buffer (10 mM ammonium bicarbonate, pH 7.4) to the original volume, followed by gentle swirling and/or vortexing to ensure adequate homogenization. If further dilution is required, please use the lyophilization buffer.

General Info

  • Alternative names
    • APC 2
    • APC2
    • Apo CII
    • APOC 2
    • ApoC II
    • APOC2
    • APOC2 protein
    • APOC2_HUMAN
    • ApoCII
    • Apolipoprotein C II
    • Apolipoprotein C II precursor
    • Apolipoprotein C2
    • ApolipoproteinCII
    • MGC75082
    see all
  • RelevanceAt least 9 distinct polymorphic forms of apolipoproteins are known. The apolipoproteins act as stabilizers of the intact lipoprotein particles. Quantitative measurements of HDL, LDL and VLDL particles in human serum are often used to estimate an individuals' relative risk of coronary heart disease. In addition, quantitative immunological measurements of certain apolipoproteins (especially A-1 and B) have been suggested to be more accurate estimators of coronary heart disease than measurements of lipoprotein particles (especially HDL and LDL). Apolipoprotein C-II (apoCII) is in found in chylomicrons (large lipoprotein particles absorbed from the gastrointestinal tract) and VLDL (large lipoproteins that are broken down to eventually form LDL). ApoCII activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells.
  • Cellular localizationSecreted

Natural Human Apolipoprotein CII images

  • SDS-PAGE analysis of ab90925 on an 18% Tris-Glycine Gel
    Lane 1: Apolipoprotein CII - 10 µg (Reduced/heated)
    Lane 2: Apolipoprotein CII - 15 µg (Reduced/heated)
    Lane 3: Molecular weight markers
    Lane 4: Apolipoprotein CII - 10 µg (Non-reduced/no heat)
    Lane 5: Apolipoprotein CII - 20 µg (Non-reduced/no heat)

References for Natural Human Apolipoprotein CII (ab90925)

ab90925 has not yet been referenced specifically in any publications.

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