Natural Human Apotransferrin protein (ab91100)

Overview

Description

  • NatureNatural
  • SourceNative
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab91100 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    Iron Content: <30 µg per gram. Purified to have less than 0.01% iron and an iron-binding capacity of 1.25 ug/mg. Sterile filtered using 0.2 micron filter.
  • FormLyophilised
  • Additional notesEndotoxin Level: <0.1 Eu per mg by LAL testing. Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Preservative: None
    Constituents: 10mM Sodium phosphate, pH 7.4

  • ReconstitutionDissolves in water at 10 mg per ml.

General Info

  • Alternative names
    • apo transferrin
    • apo-transferrin
    • aposiderophilin
    • apotransferrin
    • Beta-1 metal-binding globulin
    • ion free transferrin
    • PRO1557
    • PRO2086
    • Serotransferrin
    • Siderophilin
    • TF
    • TFQTL1
    • Transferrin
    • TRFE_HUMAN
    see all
  • FunctionTransferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
  • Tissue specificityExpressed by the liver and secreted in plasma.
  • Involvement in diseaseDefects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.
  • Sequence similaritiesBelongs to the transferrin family.
    Contains 2 transferrin-like domains.
  • Cellular localizationSecreted.
  • Information by UniProt

Natural Human Apotransferrin protein images

  • SDS-PAGE: 4-12% Bis-Tris NuPAGE gel
    Lane 1: 5 µg Apotransferrin (reduced/heated)
    Lane 2: Molecular weight markers
    Lane 3: 5 µg Apotransferrin (non-reduced/no heat)
    Lane 4: 10 µg Apotransferrin (non-reduced/no heat)
    Lane 5: 20 µg Apotransferrin (non-reduced/no heat)

References for Natural Human Apotransferrin protein (ab91100)

ab91100 has not yet been referenced specifically in any publications.

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