The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityActivity: 40-70 units per mg protein. One unit is defined as the amount of enzyme that hydrolyzes one µmole of Suc-Ala-Ala-Pro-Phe-pNA per minute at 25°C, pH 8.0
Additional notesPrepared from tissue shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20ºC.
Buffer is 2 mM HCl
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Serum calcium decreasing factor
FunctionHas chymotrypsin-type protease activity and hypocalcemic activity.
Involvement in diseaseVariations in CTRC influence susceptibility to chronic pancreatitis [MIM:167800]. Chronic pancreatitis is a persistent inflammatory disorder characterized by permanent destruction of the pancreatic parenchyma.
Sequence similaritiesBelongs to the peptidase S1 family. Elastase subfamily. Contains 1 peptidase S1 domain.