Native Human Factor XIII protein (Active) (ab62427)
Key features and details
- Expression system: Native
- Purity: > 95% Ion Exchange Chromatography
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
Description
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Product name
Native Human Factor XIII protein (Active)
See all Factor XIII proteins and peptides -
Biological activity
This product has an activity range of 80 U/mg to 130 U/mg.
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Purity
> 95 % Ion Exchange Chromatography.
Factor XIII is purified by barium citrate, ammonium sulfate and glycine precipitations, ion exchange chromatography and gel filtration. Factor XIII is homogeneous as judged by SDS PAGE. -
Expression system
Native -
Protein length
Full length protein -
Animal free
No -
Nature
Native -
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Species
Human
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab62427 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
Functional Studies
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Form
Liquid -
Additional notes
Concentration varies from lot to lot but is between 5-10mg/ml -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.
Constituents: 0.0146% EDTA, 50% Glycerol
This product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- Coagulation factor XIII B chain
- Coagulation factor XIII, A2 polypeptide
- Coagulation factor XIII, B polypeptide
see all -
Function
The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin. -
Involvement in disease
Factor XIII subunit B deficiency -
Sequence similarities
Contains 10 Sushi (CCP/SCR) domains. -
Cellular localization
Secreted. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab62427 has been referenced in 1 publication.
- Kumar L et al. Activity-dependent interdomain dynamics of matrix metalloprotease-1 on fibrin. Sci Rep 10:20615 (2020). PubMed: 33244162