The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesStarting material tested and found negative for HIV I & II antibodies, Hepatitis B surface antigen, and Hepatitis C antibodies.
Ferritin consists of a hollow shell comprising 24 light and heavy subunits, the precise ratio of which is tissue specific. Human spleen ferritin is similar to liver ferritin but contains a higher proportion of the heavy subunits.
FunctionStores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
Sequence similaritiesBelongs to the ferritin family. Contains 1 ferritin-like diiron domain.