Natural human IgE protein (ab92394)

Overview

Description

  • Nature
    Native
  • Source
    Native
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab92394 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Activity: >18,500 IU/ml (ACS: 180 standardized against WHO 2nd IRP 75/502, 1IU = 2.4ng IgE)
  • Applications

    Western blot

  • Form
    Liquid
  • Additional notes

    Human Myeloma IgE kappa from Human plasma

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Igh2
    • IGHE
    • IGHEP1
    • Immunoglobulin heavy constant epsilon
  • Relevance
    IgE is the class of antibodies produced in the lungs, skin, and mucous membranes. It may protect against parasite invasion, but it is a major factor in allergic reactions. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock.
  • Cellular localization
    Cell Membrane

Images

  • Anti-IgE antibody [XTE4] (ab7382) at 1 µg/ml + Natural human IgE protein (ab92394) at 0.01 µg

    Secondary
    Goat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 8 minutes

References

ab92394 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Thank you for your inquiry. ab92394 Human Myeloma IgE Kappa has not been tested with other molecules or antigens to determine reactivity. However, this product is neat human plasma which means that there is a possibility that it will react with o...

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This product has not been purified but it is composed of concentrated IgE in serum.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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