Native Human IgG Fab fragment protein (ab90352)
Key features and details
- Expression system: Native
- Purity: > 95% SDS-PAGE
- Suitable for: SDS-PAGE
Description
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Product name
Native Human IgG Fab fragment protein -
Purity
> 95 % SDS-PAGE. -
Expression system
Native -
Protein length
Full length protein -
Animal free
No -
Nature
Native -
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Predicted molecular weight
50 kDa
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab90352 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Additional notes
Protein Determination: Extinction Coefficient (E) 0.1% at 280nm = 1.35.
Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 0.0536% PBS, 0.87% Sodium chloride
General Info
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Relevance
Human IgG consists of four subclasses (1-4) that can be recognised by antigen differences in their heavy chains. Each subclass has different biological and physiochemical properties. The IgG subclass may be preferentially produced in response to different antigens. The Fab fragment (fragment antigen binding) is the antigen region of the IgG molecule. It is composed of one constant and one variable domain of each of the heavy and the light chain.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab90352 has been referenced in 2 publications.
- Lu CH et al. The Fc?RIII Engagement Augments PMA-Stimulated Neutrophil Extracellular Traps (NETs) Formation by Granulocytes Partially via Cross-Talk between Syk-ERK-NF-?B and PKC-ROS Signaling Pathways. Biomedicines 9:N/A (2021). PubMed: 34572313
- Naik AS et al. Humoral immune system targets clonotypic antibody-associated hepatitis C virus. J Gen Virol 98:179-189 (2017). PubMed: 28284234