Natural Human IgG2 protein (ab90284)

Overview

Description

  • NatureNatural
  • SourceNative
  • Amino Acid Sequence
    • SpeciesHuman
    • Additional sequence informationPrepared from myeloma plasma.

Associated products

Specifications

Our Abpromise guarantee covers the use of ab90284 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityShown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 and 2 by FDA approved tests.
  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Additional notes

    Extinction Coefficient (E) 0.1% at 280nm =1.36.

    Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 and 2 by FDA approved tests.  

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.05% Sodium Azide
    Constituents: 20mM PBS, 150mM Sodium chloride, pH 7.4

General Info

  • Alternative names
    • Ig gamma-2 chain C region
    • IGHG2
    • immunoglobulin Gm2
    • immunoglobulin heavy constant gamma 2 (G2m marker)
    • immunoglobulin heavy constant, gamma 2
    see all
  • RelevanceThere are four IgG subclasses (IgG1, 2, 3 and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant). IgG2 is the only IgG subclass which passes through the placenta at a level generally lower than that found in the mother. A deficiency of IgG2 indicates a poor antibody response to bacterial polysaccharides and can lead to increased susceptibility to infections caused by encapsulated bacteria.
  • Cellular localizationSecreted

References for Natural Human IgG2 protein (ab90284)

ab90284 has not yet been referenced specifically in any publications.

Product Wall




I can confirm that the light chain of this IgG2 protein is the kappa light chain.


Thank you for your email.

I am happy to check these concentrations for you. Please find here below the answers:

IgG1 protein (ab90283) you will receive 1 mg at 3.41mg/ml, ¨so it will be in 293ul



IgG2 protein...

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Thank you for contacting us. Because this IgG2 was purified from human myeloma plasma, we do not know the exact sequence. The sequence of the C region of human IgG2 can be found on the UniProt database: http://www.uniprot.org/uniprot/P01859 ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"