Overview

  • Product name
    Natural Human IgM Fc fragment protein
  • Protein length
    Full length protein

Description

  • Nature
    Native
  • Source
    Native

Specifications

Our Abpromise guarantee covers the use of ab90287 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    There is no reaction by IEP to antisera to kappa or lambda. Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 and 2 by FDA approved tests.
  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Liquid
  • Additional notes
    Extinction Coefficient (E) 0.1% at 280nm =1.18.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20mM PBS, 150mM Sodium chloride, pH 7.4

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • DKFZp686I15196
    • DKFZp686I15212
    • FLJ00385
    • MGC104996
    • MGC52291
    • MU
    • mu heavy chain constant region
    • VH
    see all
  • Relevance
    Immunoglobulin M (IgM) is produced as a 900 kDa pentamer, which is an efficient complement binder. This antibody type is produced initially in the immune response and it is the first immunoglobulin class to be synthesized by a fetus or newborn. IgM antibodies do not cross the placenta. IgM concentration in blood is 0.12 g/l and its biological survival (plasma T1/2) is 5 days.
  • Cellular localization
    Cell Membrane and Secreted

References for Natural Human IgM Fc fragment protein (ab90287)

This product has been referenced in:

See 1 Publication for this product

Product Wall

Thank you and your customer for contacting us.

I attached in image of ab90287 on a SDS gel for your customer information.

It is expected to see a double band at ca 30˜46kDa when using an denaturing/ reducing gel. This protein consis...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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