Overview

Description

  • Nature
    Native
  • Source
    Native
  • Amino Acid Sequence
    • Accession
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab98926 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    >= 96 % SDS-PAGE.

  • Form
    Lyophilised
  • Additional notes
    Starting material donor tested and found negative for HIV I & II antibodies, Hepatitis B surface antigen, Hepatitis C antibodies and Syphilis.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C.

    Preservative: None
    Constituents: 0.1M Sodium chloride, 50mM Sodium acetate buffer, pH 6.0

General Info

  • Alternative names
    • 84 kDa myeloperoxidase
    • 89 kDa myeloperoxidase
    • EC 1.11.1.7
    • EC1.11.2.2
    • fj80f04
    • MPO
    • mpx
    • myeloid-specific peroxidase
    • Myeloperoxidase
    • Myeloperoxidase heavy chain
    • Myeloperoxidase light chain
    • PERM_HUMAN
    • wu:fj80f04
    see all
  • Function
    Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
  • Involvement in disease
    Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
  • Sequence similarities
    Belongs to the peroxidase family. XPO subfamily.
  • Cellular localization
    Lysosome.
  • Information by UniProt

References for Natural Human Myeloperoxidase protein (ab98926)

This product has been referenced in:
  • Moral-Vico J  et al. Dual chronoamperometric detection of enzymatic biomarkers using magnetic beads and a low-cost flow cell. Biosens Bioelectron 69:328-36 (2015). Read more (PubMed: 25791338) »
  • Herrasti Z  et al. Carbon nanotube wiring for signal amplification of electrochemical magneto immunosensors: application to myeloperoxidase detection. Anal Bioanal Chem 406:5487-93 (2014). Read more (PubMed: 24994664) »

See all 3 Publications for this product

Product Wall

Gracias por contactarnos.

El anticuerpo ab24467 puede alicuortarse sin ningún problema. Sin embargo, la enzima HRP es muy sensible a los ciclos de congelación / descongelación, por lo que no se aconseja mantenerla a -20C....

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Thank you for your inquiry.

I can confirm that the specific activity of ab98926 is lot dependent.

The lot that is in stock at the moment has the specific activity of: 340 units/mg.

I hope this information is helpful and wi...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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