Natural human PF4 protein (ab80477)

Overview

Description

  • NatureNatural
  • SourceNative
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab80477 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activitySpecific activity: 115 Units/mg (1 unit will neutralize 1 IU of heparin in 1ml of normal plasma).
  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    ab80477 is purified by Heparin-agarose affinity chromatography.
  • FormLiquid
  • Additional notesIsoelectric Point: 7.6.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 2M Sodium chloride, 20mM Tris, pH 7.4

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • C-X-C motif chemokine 4
    • Chemokine (C X C motif) ligand 4
    • Chemokine (CXC motif) ligand 4
    • CXCL 4
    • CXCL4
    • Iroplact
    • MGC138298
    • Oncostatin A
    • Oncostatin-A
    • OncostatinA
    • PF 4
    • PF-4
    • PF4
    • Platelet factor 4
    • PLF4_HUMAN
    • SCYB 4
    • SCYB4
    • short form
    • Small inducible cytokine subfamily member 4
    see all
  • FunctionReleased during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.
  • Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications
    Binds non-covalently to a proteoglycan molecule.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Natural human PF4 protein (ab80477)

ab80477 has not yet been referenced specifically in any publications.

Product Wall

Thank you very much for confirming the details.

The product ab80477 is available for shipping. The cost is €465 plus €42 delivery charges. The product will be delivered by FedEX by overnight delivery.

The product ab81754 i...

Read More

Thank you for contacting us.

ELISA application is not tested with these products however because these are full length protein so these may be used.

"ELISA assay for HIT detection" could you please explain how will be using...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"