Natural Human Serum Albumin protein (FITC) (ab8030)

Overview

Description

  • NatureNatural
  • SourceNative
  • ConjugationFITC. Ex: 493nm, Em: 528nm

Specifications

Our Abpromise guarantee covers the use of ab8030 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Flow Cytometry

    Immunomicroscopy

  • FormLyophilised
  • Additional notes

    Fluorochrome/Protein Ratio: 1.5 moles FITC per mole of Human Albumin

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C. Avoid freeze / thaw cycle.

    Preservative: 0.01% Sodium Azide
    Constituents: 10mg/ml Polyethylene Glycol, 0.15M Sodium Chloride, 0.02M Potassium Phosphate. pH 7.2

  • ReconstitutionReconstitue with 1.0 mL of deionized water

General Info

  • Alternative names
    • alb
    • ALBU_HUMAN
    • Albumin
    • Albumin (32 AA)
    • Albumin (AA 34)
    • Analbuminemia
    • Bisalbuminemia
    • Cell growth inhibiting protein 42
    • DKFZp779N1935
    • Dysalbuminemic hyperthyroxinemia
    • Growth inhibiting protein 20
    • HSA
    • Hyperthyroxinemia dysalbuminemic
    • PRO0883
    • PRO0903
    • PRO1341
    • Serum albumin
    see all
  • FunctionSerum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
  • Tissue specificityPlasma.
  • Involvement in diseaseDefects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
  • Sequence similaritiesBelongs to the ALB/AFP/VDB family.
    Contains 3 albumin domains.
  • Post-translational
    modifications
    Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
    Glycated in diabetic patients.
    Phosphorylation sites are present in the extracelllular medium.
    Acetylated on Lys-223 by acetylsalicylic acid.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Natural Human Serum Albumin protein (FITC) (ab8030)

This product has been referenced in:
  • Zadravec P  et al. Development of Recombinant Lactococcus lactis Displaying Albumin-Binding Domain Variants against Shiga Toxin 1 B Subunit. PLoS One 11:e0162625 (2016). ELISA . Read more (PubMed: 27606705) »

See 1 Publication for this product

Product Wall

Our product number AB8030, Human Serum Albumin (FITC), contains only 10mg/ml Polyethylene Glycol, 0.15M Sodium Chloride, 0.02M Potassium Phosphate. pH 7.2 as a storage buffer.

I have heard back from the lab about whether the FITC tag alters the structure of the protein. They have told me that we do not have specific data on how the FITC tag affects the protein structure, but they have seen data experiments using a monoclonal...

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I am still waiting to hear from the lab about any possible structural alterations to HSA when FITC tagged. In regards to the quote that you requested, we are in the process of generating that quote but I just need to confirm you address and contact ph...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"