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- Amino Acid Sequence
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Biological activity
Activity: 210,000 IU/mg (Relative to WHO International Standard for Human High Molecular Weight Urokinase, NIBSC 87/594)
- Purity> 95
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Preparation and Storage
- Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 50mM Sodium acetate, 100mM Sodium chloride, 1mM EDTA, pH 5
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- FunctionSpecifically cleave the zymogen plasminogen to form the active enzyme plasmin.
- Tissue specificityExpressed in the prostate gland and prostate cancers.
- Sequence similaritiesBelongs to the peptidase S1 family.
Contains 1 EGF-like domain.
Contains 1 kringle domain.
Contains 1 peptidase S1 domain.
modificationsPhosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding.
- Cellular localizationSecreted.
Information by UniProt
References for Natural human Urokinase protein (ab92737)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"