The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesAll human source materials have tested negative for HIV 1 and HIV 2 and non-reactive for HBsAg, anti-HCV and anti-HBc by FDA required tests. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
ReconstitutionReconstitute with 227ul distilled water.
Group specific component
Group specific component vitamin D binding protein
Vitamin D binding alpha globulin
Vitamin D-binding protein
FunctionMultifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
Sequence similaritiesBelongs to the ALB/AFP/VDB family. Contains 3 albumin domains.
References for Natural Human Vitamin D Binding protein (ab77899)
This product has been referenced in:
Behrouz GF et al. Presence of auto-antibody against two placental proteins, annexin A1 and vitamin D binding protein, in sera of women with pre-eclampsia. J Reprod Immunol99:10-6 (2013).
Read more (PubMed: 23830177) »
Sohn DH et al. Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4. Arthritis Res Ther14:R7 (2012).
Read more (PubMed: 22225630) »