The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. Purity: greater than 98% as determined by: analysis by RP-HPLC and analysis by SDS-PAGE.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 5% Mannitol and 1% HSA
This product is an active protein and may elicit a biological response in vivo, handle with caution.
ReconstitutionReconstitute in sterile 18MOhms/cm water, to not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Beta nerve growth factor
Beta-nerve growth factor
Nerve growth factor
Nerve growth factor (beta polypeptide)
Nerve growth factor beta
Nerve growth factor beta polypeptide
Nerve growth factor beta subunit
FunctionNerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
Involvement in diseaseNeuropathy, hereditary sensory and autonomic, 5
Sequence similaritiesBelongs to the NGF-beta family.