Overview

Description

  • NatureNatural
  • SourceNative
  • Amino Acid Sequence
    • SpeciesPig

Specifications

Our Abpromise guarantee covers the use of ab95111 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityab95111 cleaves PAI-1 between the P3 and P4 residues to create a loop-inserted species that is non-inhibitory towards the target enzymes uPA and tPA. It can be used to cleave Human PAI-1 in any application requiring elastase cleavage.
  • Applications

    Functional Studies

  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Additional notesab95111 cleaves PAI-1 between the P3 and P4 residues to create a loop-inserted species that is non-inhibitory towards the target enzymes uPA and tPA. It can be used to cleave Human PAI-1 in any application requiring elastase cleavage.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1M Sodium chloride, 0.1M HEPES, pH 7.4

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • CEL3A_HUMAN
    • CELA3A
    • Chymotrypsin-like elastase family member 3A
    • ELA1
    • ELA2A
    • ELA2B
    • ELA3
    • ELA3A
    • ELA3B
    • Elastase 1
    • Elastase 2A
    • Elastase 2B
    • Elastase 3A
    • Elastase 3A pancreatic
    • Elastase 3B
    • Elastase 3B pancreatic
    • Elastase IIIA
    • Elastase IIIB
    • Elastase-3A
    • Fecal pancreatic elastase 1
    • HLE
    • Medullasin
    • Pancreatic elastase IIA
    • PE 1
    • PE1
    • Protease E
    see all
  • FunctionEfficient protease with alanine specificity but only little elastolytic activity.
  • Sequence similaritiesBelongs to the peptidase S1 family. Elastase subfamily.
    Contains 1 peptidase S1 domain.
  • Information by UniProt

References for Natural pig Elastase protein (ab95111)

ab95111 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"