Overview

Description

  • Nature
    Native
  • Source
    Native
  • Amino Acid Sequence
    • Accession
      P49065
    • Species
      Rabbit
    • Sequence
      EAHKSEIAHRFNDVGEEHFIGLVLITFSQYLQKCPYEEHAKLVKEVTDLA KACVADESAANCDKSLHDIFGDKICALPSLRDTYGDVADCCEKKEPERNE CFLHHKDDKPDLPPFARPEADVLCKAFHDDEKAFFGHYLYEVARRHPYFY APELLYYAQKYKAILTECCEAADKGACLTPKLDALEGKSLISAAQERLRC ASIQKFGDRAYKAWALVRLSQRFPKADFTDISKIVTDLTKVHKECCHGDL LECADDRADLAKYMCEHQETISSHLKECCDKPILEKAHCIYGLHNDETPA GLPAVAEEFVEDKDVCKNYEEAKDLFLGKFLYEYSRRHPDYSVVLLLRLG KAYEATLKKCCATDDPHACYAKVLDEFQPLVDEPKNLVKQNCELYEQLGD YNFQNALLVRYTKKVPQVSTPTLVEISRSLGKVGSKCCKHPEAERLPCVE DYLSVVLNRLCVLHEKTPVSEKVTKCCSESLVDRRPCFSALGPDETYVPK EFNAETFTFHADICTLPETERKIKKQTALVELVKHKPHATNDQLKTVVGE FTALLDKCCSAEDKEACFAVEGPKLVESSKATLG
    • Molecular weight
      66 kDa
    • Amino acids
      25 to 608
    • Additional sequence information
      Prepared from rabbit plasma.

Specifications

Our Abpromise guarantee covers the use of ab188055 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    >95% by SDS-PAGE .
    ab188055 is prepared by proprietary fractionation methods.
  • Form
    Lyophilised
  • Additional notes

    Extinction Coefficient: 0.67.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -80°C.

    Salt free.

  • Reconstitution
    Add deionized water or buffer to original or desired volume, aliquot and freeze unused portion. (50 ml before lyophilisation).

General Info

  • Alternative names
    • alb
    • ALBU_HUMAN
    • Albumin (32 AA)
    • Albumin (AA 34)
    • cell growth inhibiting protein 42
    • DKFZp779N1935
    • GIG20
    • GIG42
    • growth-inhibiting protein 20
    • OTTHUMP00000220436
    • OTTHUMP00000220438
    • OTTHUMP00000220439
    • PRO0883
    • PRO0903
    • PRO1341
    • PRO1708
    • PRO2044
    • PRO2619
    • PRO2675
    • Serum albumin
    • UNQ696/PRO1341
    see all
  • Function
    Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
  • Tissue specificity
    Plasma.
  • Involvement in disease
    Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
  • Sequence similarities
    Belongs to the ALB/AFP/VDB family.
    Contains 3 albumin domains.
  • Post-translational
    modifications
    Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
    Glycated in diabetic patients.
    Phosphorylation sites are present in the extracelllular medium.
    Acetylated on Lys-223 by acetylsalicylic acid.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab188055 has not yet been referenced specifically in any publications.

Publishing research using ab188055? Please let us know so that we can cite the reference in this datasheet.

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