The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesWB: Use at a concentration of 1 - 4 µg/ml. Predicted molecular weight: 40 kDa. Exposure times of 30 - 60 minutes may be required for detection at lower concentrations.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionComponent of the NADPH-oxidase, a multicomponent enzyme system responsible for the oxidative burst in which electrons are transported from NADPH to molecular oxygen, generating reactive oxidant intermediates. It may be important for the assembly and/or activation of the NADPH-oxidase complex.
Tissue specificityExpression is restricted to hematopoietic cells.