Overview

  • Product name
  • Description
    Rabbit polyclonal to NCKAP1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Xenopus laevis, Zebrafish
  • Immunogen

    Recombinant fragment, corresponding to a region within N terminal amino acids 2-298 of Human NCKAP1 (Q9Y2A7).

  • Positive control
    • NT2D1, IMR32, U-87 MG, MCF7 whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab126061 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 128 kDa.

Target

  • Function
    Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1.
  • Tissue specificity
    Expressed in all tissues examined except peripheral blood leukocytes, with highest expression in brain, heart, and skeletal muscle.
  • Sequence similarities
    Belongs to the HEM-1/HEM-2 family.
  • Cellular localization
    Cell membrane. Cell projection > lamellipodium membrane. At the interface between the lamellipodial actin meshwork and the membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ11291 antibody
    • KIAA0587 antibody
    • Membrane associated protein HEM2 antibody
    • Membrane-associated protein HEM-2 antibody
    • MGC8981 antibody
    • NAP 1 antibody
    • NAP1 antibody
    • NAP125 antibody
    • NCK associated protein 1 antibody
    • NCK associated protein antibody
    • Nck-associated protein 1 antibody
    • Nckap1 antibody
    • NCKP1_HUMAN antibody
    • OTTHUMP00000163460 antibody
    • OTTHUMP00000163461 antibody
    • p125Nap1 antibody
    see all

Images

  • Anti-NCKAP1 antibody (ab126061) at 1/1000 dilution + U-87 MG whole cell lysate at 30 µg

    Predicted band size : 128 kDa

References

ab126061 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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