Overview

  • Product nameAnti-NCKX2 antibody
    See all NCKX2 primary antibodies
  • Description
    Rabbit polyclonal to NCKX2
  • SpecificityDetects rat sodium / calcium - potassium exchanger (NCKX 2) overexpressed in HEK cells transfected with the rat gene. By Western blot, the NCX2 antibody detects the recombinant rat protein (78kDa). Immunohistochemical staining of rat NCX2 in HEK cells transfected with the rat gene results in staining of the plasma membrane.
  • Tested applicationsSuitable for: WB, IP, ICC/IF, IHC-Frmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Rat NCKX2 aa 90-102 (extracellular).
    Sequence:

    DLNDKIRDYTPQP


    (Peptide available as ab5896)

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab3507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100. Predicted molecular weight: 74 kDa.Can be blocked with NCKX2 peptide (ab5896).
IP Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.
IHC-Fr 1/100.

Target

  • FunctionCritical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
  • Sequence similaritiesBelongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Na(+)/K(+)/Ca(2+) exchange protein 2 antibody
    • Na(+)/K(+)/Ca(2+)-exchange protein 2 antibody
    • NCKX 2 antibody
    • NCKX2_HUMAN antibody
    • OTTHUMP00000045115 antibody
    • Retinal cone Na Ca+K exchanger antibody
    • Retinal cone Na-Ca+K exchanger antibody
    • Slc24a2 antibody
    • Sodium/potassium/calcium exchanger 2 antibody
    • Solute carrier family 24 (sodium/potassium/calcium exchanger) member 2 antibody
    • Solute carrier family 24 member 2 antibody
    see all

Anti-NCKX2 antibody images

  • ab3507 staining NCKX2 in Rat brain tissue section by Immunohistochemistry (Frozen sections).



  • Predicted band size : 74 kDa

    Western blot detection of NCKX2 in Rat brain using ab3507.

References for Anti-NCKX2 antibody (ab3507)

ab3507 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab3507.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"