Overview

  • Product nameNCKX2 peptide

Description

  • NatureSynthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab5896 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Additional notes


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat Excanger (Na/Ca-k), catalog ab3507. Using a solution with equal weights per unit volume of peptide and corresponding antibody will yield a solution with a large molar excess of peptide that is able to competitively bind the antibody.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • Na(+)/K(+)/Ca(2+) exchange protein 2
    • Na(+)/K(+)/Ca(2+)-exchange protein 2
    • NCKX 2
    • NCKX2_HUMAN
    • OTTHUMP00000045115
    • Retinal cone Na Ca+K exchanger
    • Retinal cone Na-Ca+K exchanger
    • Slc24a2
    • Sodium/potassium/calcium exchanger 2
    • Solute carrier family 24 (sodium/potassium/calcium exchanger) member 2
    • Solute carrier family 24 member 2
    see all
  • FunctionCritical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
  • Sequence similaritiesBelongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.
  • Cellular localizationMembrane.
  • Information by UniProt

References for NCKX2 peptide (ab5896)

ab5896 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"