Overview

  • Product name
    Anti-NCR2 antibody [8F12]
    See all NCR2 primary antibodies
  • Description
    Mouse monoclonal [8F12] to NCR2
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 19-130 of Human NCR2

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.02% Thimerosal (merthiolate)
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    8F12
  • Myeloma
    Sp2/0
  • Isotype
    IgG3
  • Light chain type
    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab25911 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
WB 1/1000 - 1/2000. Predicted molecular weight: 31 kDa.

Target

  • Function
    Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
  • Tissue specificity
    Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells.
  • Sequence similarities
    Belongs to the natural cytotoxicity receptor (NCR) family.
    Contains 1 Ig-like (immunoglobulin-like) domain.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activating NK receptor NKp44 antibody
    • CD336 antibody
    • CD336 antigen antibody
    • dJ149M18.1 antibody
    • LY95 antibody
    • Lymphocyte antigen 95 (activating NK receptor; NK p44) antibody
    • Lymphocyte antigen 95 homolog (activating NK receptor; NK p44) antibody
    • Lymphocyte antigen 95 homolog antibody
    • Lymphocyte antigen 95, mouse, homolog of antibody
    • Natural cytotoxicity triggering receptor 2 antibody
    • Natural killer cell p44 related protein antibody
    • Natural killer cell p44-related protein antibody
    • NCR2 antibody
    • NCTR2_HUMAN antibody
    • NK cell activating receptor (NKp44) antibody
    • NK cell activating receptor antibody
    • NK cell-activating receptor antibody
    • NK p44 antibody
    • NK-p44 antibody
    • NKp44 antibody
    see all

Images

  • All lanes : Anti-NCR2 antibody [8F12] (ab25911) at 1/1000 dilution

    Lane 1 : recombinant human NKp30
    Lane 2 : recombinant human NCR2 (NKp44) fragment aa 19-130. (~16kDa)
    Lane 3 : recombinant human NKp46

    Lysates/proteins at 0.02 µg per lane.

    Secondary
    goat anti-mouse secondary antibody conjugated to HRP

    Predicted band size : 31 kDa
    Observed band size : ~12 kDa (why is the actual band size different from the predicted?)

References

ab25911 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab25911.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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