Overview

  • Product nameAnti-NDRG2 antibody
    See all NDRG2 primary antibodies
  • Description
    Goat polyclonal to NDRG2
  • Specificityab113439 is expected to recognize reported isoform a (NP_963293.1) only. Reported variants represent identical protein: NP_963831.1, NP_963293.1, NP_963834.1, NP_963833.1.
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Horse, Dog
  • Immunogen

    Synthetic peptide corresponding to Human NDRG2 aa 25-39 (N terminal).
    Sequence:

    KEAELAARILLDQGQ-C


    Database link: Q9UN36

  • Positive control
    • Human Brain (Temporal Cortex), Mouse and Rat Brain lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab113439 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.

Antibody detection limit dilution 1:16,000.

WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 41 kDa).

Target

  • FunctionMay be involved in dendritic cell and neuron differentiation. May have anti-tumor activity.
  • Tissue specificityHighly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues; absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level).
  • Sequence similaritiesBelongs to the NDRG family.
  • Developmental stageSpecifically expressed during dendritic cell differentiation (in vitro). Expression is low in fetal brain and increases during brain postnatal development.
  • Cellular localizationCytoplasm. Cytoplasm > perinuclear region. Perinuclear in neurons.
  • Information by UniProt
  • Database links
  • Alternative names
    • Antidepressant related protein ADRG123 antibody
    • Cytoplasmic protein Ndr1 antibody
    • DKFZp781G1938 antibody
    • FLJ25522 antibody
    • KIAA1248 antibody
    • N myc downstream regulated gene 2 antibody
    • N myc downstream regulator 2 antibody
    • NDR1 related protein NDR2 antibody
    • NDRG 2 antibody
    • NDRG family member 2 antibody
    • NDRG1 related protein antibody
    • NDRG2 antibody
    • NDRG2_HUMAN antibody
    • Protein NDRG2 antibody
    • Protein Syld709613 antibody
    • SYLD antibody
    • Syld709613 protein antibody
    see all

Anti-NDRG2 antibody images

  • All lanes : Anti-NDRG2 antibody (ab113439) at 0.3 µg/ml

    Lane 1 : Mouse Brain lysate
    Lane 2 : Rat Brain lysate

    Lysates/proteins at 35 µg per lane.


    Predicted band size : 41 kDa
  • Anti-NDRG2 antibody (ab113439) at 0.1 µg/ml + Human Temporal Cortex lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 41 kDa

References for Anti-NDRG2 antibody (ab113439)

ab113439 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab113439.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"