Overview

  • Product nameAnti-NDRG2 antibody
    See all NDRG2 primary antibodies
  • Description
    Mouse monoclonal to NDRG2
  • Tested applicationsSuitable for: WB, ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: MAELQEVQIT EEKPLLPGQT PEAAKTHSVE TPYGSVTFTV YGTPKPKRPA ILTYHDVGLN YKSCFQPLFQ FEDMQEIIQN FVRVHVDAPG MEEGAP, corresponding to amino acids 1-97 of Human NDRG2

Properties

Applications

Our Abpromise guarantee covers the use of ab57429 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 41 kDa.
ICC/IF Use at an assay dependent concentration. PubMed: 23800335
IHC-P Use at an assay dependent concentration. PubMed: 23800335

Target

  • FunctionMay be involved in dendritic cell and neuron differentiation. May have anti-tumor activity.
  • Tissue specificityHighly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues; absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level).
  • Sequence similaritiesBelongs to the NDRG family.
  • Developmental stageSpecifically expressed during dendritic cell differentiation (in vitro). Expression is low in fetal brain and increases during brain postnatal development.
  • Cellular localizationCytoplasm. Cytoplasm > perinuclear region. Perinuclear in neurons.
  • Information by UniProt
  • Database links
  • Alternative names
    • Antidepressant related protein ADRG123 antibody
    • Cytoplasmic protein Ndr1 antibody
    • DKFZp781G1938 antibody
    • FLJ25522 antibody
    • KIAA1248 antibody
    • N myc downstream regulated gene 2 antibody
    • N myc downstream regulator 2 antibody
    • NDR1 related protein NDR2 antibody
    • NDRG 2 antibody
    • NDRG family member 2 antibody
    • NDRG1 related protein antibody
    • NDRG2 antibody
    • NDRG2_HUMAN antibody
    • Protein NDRG2 antibody
    • Protein Syld709613 antibody
    • SYLD antibody
    • Syld709613 protein antibody
    see all

Anti-NDRG2 antibody images



  • Predicted band size : 41 kDa
    NDRG2 antibody (ab57429) at 1ug/lane + HeLa cell lysate at 25ug/lane.

References for Anti-NDRG2 antibody (ab57429)

This product has been referenced in:
  • Wu Z  et al. Adenovirus-mediated NDRG2 inhibits the proliferation of human renal cell carcinoma cell line OS-RC-2 in vitro. Cell Biochem Biophys 70:593-600 (2014). Human . Read more (PubMed: 24839115) »
  • Cao W  et al. Low expression of N-myc downstream-regulated gene 2 in oesophageal squamous cell carcinoma correlates with a poor prognosis. BMC Cancer 13:305 (2013). WB, IHC-P, ICC/IF ; Human . Read more (PubMed: 23800335) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"