Anti-NDST2 antibody - N-terminal (ab191613)
Key features and details
- Rabbit polyclonal to NDST2 - N-terminal
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-NDST2 antibody - N-terminal
See all NDST2 primary antibodies -
Description
Rabbit polyclonal to NDST2 - N-terminal -
Host species
Rabbit -
Specificity
At least two isoforms of NDST2 are known to exist; ab191613 will only detect the larger isoform. ab191613 is predicted not to cross-react with other members of the NDST protein family. -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Synthetic peptide corresponding to Human NDST2 (N terminal). (16 amino acids). NP_003626.
Database link: P52849 -
Positive control
- WB: A20 cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab191613 is affinity chromatography purified via peptide column. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab191613 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 101 kDa (predicted molecular weight: 101 kDa).
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Notes |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 101 kDa (predicted molecular weight: 101 kDa). |
Target
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Function
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. -
Pathway
Glycan metabolism; heparan sulfate biosynthesis.
Glycan metabolism; heparin biosynthesis. -
Sequence similarities
Belongs to the sulfotransferase 1 family. NDST subfamily. -
Cellular localization
Golgi apparatus membrane. - Information by UniProt
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Database links
- Entrez Gene: 17423 Mouse
- SwissProt: P52850 Mouse
- Unigene: 4084 Mouse
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Alternative names
- [Heparan sulfate]-glucosamine N-sulfotransferase antibody
- bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 antibody
- Glucosaminyl N-deacetylase/N-sulfotransferase 2 antibody
see all
Images
Protocols
Datasheets and documents
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Datasheet download
References (0)
ab191613 has not yet been referenced specifically in any publications.