Anti-NDST2 antibody - N-terminal (ab191613)

Overview

  • Product name
    Anti-NDST2 antibody - N-terminal
    See all NDST2 primary antibodies
  • Description
    Rabbit polyclonal to NDST2 - N-terminal
  • Specificity
    At least two isoforms of NDST2 are known to exist; ab191613 will only detect the larger isoform. ab191613 is predicted not to cross-react with other members of the NDST protein family.
  • Tested applications
    Suitable for: ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human NDST2 (N terminal). (16 amino acids). NP_003626.
    Database link: P52849

  • Positive control
    • A20 cell lysate; Daudi cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab191613 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 101 kDa (predicted molecular weight: 101 kDa).

Target

  • Function
    Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate.
  • Pathway
    Glycan metabolism; heparan sulfate biosynthesis.
    Glycan metabolism; heparin biosynthesis.
  • Sequence similarities
    Belongs to the sulfotransferase 1 family. NDST subfamily.
  • Cellular localization
    Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • [Heparan sulfate]-glucosamine N-sulfotransferase antibody
    • bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 antibody
    • Glucosaminyl N-deacetylase/N-sulfotransferase 2 antibody
    • glucosaminyl N-deacetylase/N-sulphotransferase 2 antibody
    • heparan glucosaminyl N-deacetylase/N-sulfotransferase 2 antibody
    • heparan N-sulfotransferase 2 antibody
    • heparan sulfate N-deacetylase/N-sulfotransferase 2 antibody
    • Heparan sulfate N-sulfotransferase 2 antibody
    • HSST2 antibody
    • mastocytoma N-deacetylase/N-sulfotransferase antibody
    • Mndns antibody
    • N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 antibody
    • N-heparan sulfate sulfotransferase 2 antibody
    • N-HSST 2 antibody
    • NDST-2 antibody
    • NDST2 antibody
    • NDST2_HUMAN antibody
    • NST2 antibody
    see all

Images

  • All lanes : Anti-NDST2 antibody - N-terminal (ab191613) at 1 µg/ml

    Lane 1 : A20 cell lysate
    Lane 2 : A20 cell lysate with blocking peptide

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 101 kDa
  • Immunofluorescent analysis of Daudi cell labeling NDST2 with ab191613 at 20 μg/ml.

References

ab191613 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab191613.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up