Overview

  • Product name
  • Description
    Rabbit polyclonal to NDUAB
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 71-100 of Human NDUAB (NP_783313.1), conjugated to KLH.

  • Positive control
    • Y79 cell line lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab107972 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 15 kDa.

Target

  • Function
    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
  • Involvement in disease
    Defects in NDUFA11 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical manifestations, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy and some forms of Parkinson disease.
  • Sequence similarities
    Belongs to the complex I NDUFA11 subunit family.
  • Cellular localization
    Mitochondrion inner membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2010012C24Rik antibody
    • AV006275 antibody
    • B14.7 antibody
    • CI-B14.7 antibody
    • Complex I-B14.7 antibody
    • FLJ76501 antibody
    • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa antibody
    • NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 antibody
    • NADH-ubiquinone oxidoreductase subunit B14.7 antibody
    • NDUAB_HUMAN antibody
    • Ndufa11 antibody
    see all

Images

  • Anti-NDUAB antibody (ab107972) at 1/100 dilution + Y79 cell line lysates at 35 µg

    Predicted band size : 15 kDa

References

ab107972 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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