Overview

  • Product nameAnti-NDUF3 antibody
  • Description
    Rabbit polyclonal to NDUF3
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    LLEPRIEIVV VGTGDRTERL QSQVLQAMRQ RGIAVEVQDT PNACATFNFL CHEGRVTGAA LIPPPGGTSL TSLGQAAQ, corresponding to amino acids 107-184 of Human NDUF3

  • Positive control
    • RT-4, U-251 MG, Human liver and tonsil lysate. Human duodenum tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab122270 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/250 - 1/500.
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionEssential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
  • Involvement in diseaseDefects in NDUFAF3 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.
  • Cellular localizationNucleus. Mitochondrion inner membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C3orf60 antibody
    • NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 antibody
    • NDUF3_HUMAN antibody
    • ndufaf3 antibody

Anti-NDUF3 antibody images

  • All lanes : Anti-NDUF3 antibody (ab122270) at 1/250 dilution

    Lane 1 : RT-4 lysate
    Lane 2 : U251 -MG lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate
  • ab122270, at 1/50 dilution, staining NDUF3 in Paraffin-embedded Human duodenum tissue by Immunohistochemistry.

References for Anti-NDUF3 antibody (ab122270)

ab122270 has not yet been referenced specifically in any publications.

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