Overview

  • Product nameAnti-NDUFS2 antibody
    See all NDUFS2 primary antibodies
  • Description
    Rabbit polyclonal to NDUFS2
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    KLH conjugated synthetic peptide corresponding to a region within internal sequence amino acids 293-323 of Human NDUFS2.

  • Positive control
    • Hela cell lysate; Mouse brain tissue lysate; Hepatocarcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab103024 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 52 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionCore subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
  • Involvement in diseaseDefects in NDUFS2 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.
  • Sequence similaritiesBelongs to the complex I 49 kDa subunit family.
  • Cellular localizationMitochondrion inner membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CI 49 antibody
    • CI 49kD antibody
    • CI-49kD antibody
    • Complex 1, mitochondrial respiratory chain, 49 KD subunit antibody
    • Complex I 49kD antibody
    • Complex I 49kDa subunit antibody
    • Complex I-49kD antibody
    • mitochondrial antibody
    • NADH dehydrogenase (ubiquinone) Fe S protein 2 49kDa antibody
    • NADH dehydrogenase (ubiquinone) Fe S protein 2, 49kDa (NADH coenzyme Q reductase) antibody
    • NADH dehydrogenase [ubiquinone] iron sulfur protein 2, mitochondrial antibody
    • NADH dehydrogenase [ubiquinone] iron-sulfur protein 2 antibody
    • NADH ubiquinone oxidoreductase 49 kDa subunit antibody
    • NADH ubiquinone oxidoreductase NDUFS2 subunit antibody
    • NADH-ubiquinone oxidoreductase 49 kDa subunit antibody
    • NADH:ubiquinone oxidoreductase core subunit S2 antibody
    • Ndufs2 antibody
    • NDUS2_HUMAN antibody
    see all

Anti-NDUFS2 antibody images

  • Anti-NDUFS2 antibody (ab103024) at 1/100 dilution + Hela cell lysate at 35 µg

    Predicted band size : 52 kDa
  • Anti-NDUFS2 antibody (ab103024) at 1/100 dilution + Mouse brain tissue lysate at 35 µg

    Predicted band size : 52 kDa
  • ab103024, at 1/50 dilution, staining NDUFS2 in formalin-fixed, paraffin-embedded hepatocarcinoma by Immunohistochemistry using a peroxidase conjugated secondary antibody and DAB staining.

References for Anti-NDUFS2 antibody (ab103024)

ab103024 has not yet been referenced specifically in any publications.

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DISCOUNT CODE: ***
Expiration date: January 11, 2013

This code will give you 1 free primary antibody before the expiration date. To redeem this offer, please submit an Abreview forab103024 in IPand include this code in the “Additio...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"