Overview

  • Product nameAnti-NDUFS8 antibody
    See all NDUFS8 primary antibodies
  • Description
    Mouse polyclonal to NDUFS8
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length NDUFS8 protein (Human)

  • Positive control
    • 293T cell lysate

Applications

Our Abpromise guarantee covers the use of ab67106 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 24 kDa (predicted molecular weight: 24 kDa).

Target

  • FunctionCore subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). May donate electrons to ubiquinone.
  • Involvement in diseaseDefects in NDUFS8 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.
  • Sequence similaritiesBelongs to the complex I 23 kDa subunit family.
    Contains 2 4Fe-4S ferredoxin-type domains.
  • Cellular localizationMitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • CI 23kD antibody
    • CI-23kD antibody
    • Complex I 23kD antibody
    • Complex I-23kD antibody
    • EC 1.6.5.3 antibody
    • EC 1.6.99.3 antibody
    • Human mitochondrial NADH dehydrogenase ubiquinone Fe S protein 8 antibody
    • NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial antibody
    • NADH ubiquinone oxidoreductase 23 kDa subunit antibody
    • NADH-ubiquinone oxidoreductase 23 kDa subunit antibody
    • NDUFS8 antibody
    • NDUS8_HUMAN antibody
    • TYKY antibody
    • TYKY subunit antibody
    • Ubiquinoneiron sulfur protein 8, mitochondrial precursor antibody
    see all

Anti-NDUFS8 antibody images

  • All lanes : Anti-NDUFS8 antibody (ab67106) at 1/500 dilution

    Lane 1 : NDUFS8 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg/ml per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 24 kDa
    Observed band size : 24 kDa

References for Anti-NDUFS8 antibody (ab67106)

ab67106 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"