This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Overview

  • Product nameAnti-Nebulette antibody
    See all Nebulette primary antibodies
  • Description
    Goat polyclonal to Nebulette

    This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

  • Specificityab99420 is expected to recognize isoform 2 and isoform 3 (NP_998734.1; NP_001166955.1) only, but does not recognize isoform 1 (NP_006384.1).
  • Species reactivity

    Predicted to work with: Mouse, Dog, Human
  • Immunogen

    Synthetic peptide:

    C-ELQRLKRTQE

    , corresponding to internal sequence amino acids 106-115 of Human Nebulette (NP_998734.1; NP_001166955.1).

Properties

Applications

Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 116 kDa. Preliminary experiments gave an approximate 30 kDa band in Human brain (frontal cortex) lysates, but not in Human, Mouse and Rat heart lysates after 1 µg/ml antibody staining. This protein has a calculated MW of 31.2 kDa according to NP_998734.1. The 30 kDa band was successfully blocked by incubation with the immunizing peptide.

Target

  • RelevanceNebulette binds to actin and plays an important role in Z-disk assembly. It is a cardiac homolog of nebulin and its expression is abundant in cardiac muscle. Nebulette defects are assocated with non-familial idiopathic cardiacmyopathy
  • Cellular localizationCytoplasmic
  • Database links
  • Alternative names
    • 1200007O21Rik antibody
    • A630080F05Rik antibody
    • Actin binding Z disk protein antibody
    • bA56H7.1 antibody
    • BB140644 antibody
    • D830029A09Rik antibody
    • LIM nebulette antibody
    • LNEBL antibody
    • MGC118387 antibody
    • NEBL antibody
    see all

References for Anti-Nebulette antibody (ab99420)

ab99420 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"