Overview

  • Product name
    Anti-Nectin 2 antibody [R2.525]
    See all Nectin 2 primary antibodies
  • Description
    Mouse monoclonal [R2.525] to Nectin 2
  • Specificity
    Recognises CD112 Poliovirus Receptor Related 2 (PRR2), a new surface molecule, which has been reported to be homologous to the poliovirus receptor (CD155). Studies demonstrate that PRR2 expression is restrictred to the myelo-monocytic and megakaryocytic lineages. PRR2 expression has also been detected on haematopoeitic progenitors expressing CD34.
  • Tested applications
    Suitable for: Flow Cyt, IHC-Fr, IPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    The details of the immunogen for this antibody are not available.

Properties

Applications

Our Abpromise guarantee covers the use of ab23601 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
IHC-Fr
IP
  • Application notes
    Flow Cyt: Use diluted between 1/50 - 100 with 10µl for 106 cells.
    IHC-Fr: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Probable cell adhesion protein.
    • Tissue specificity
      Ubiquitous.
    • Sequence similarities
      Belongs to the nectin family.
      Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD 112 antibody
      • CD112 antibody
      • CD112 antigen antibody
      • Herpes virus entry mediator B antibody
      • Herpes virus entry protein B antibody
      • Herpesvirus entry mediator B antibody
      • Herpesvirus entry protein B antibody
      • Hve B antibody
      • HveB antibody
      • Nectin-2 antibody
      • Nectin2 antibody
      • Poliovirus receptor like 2 antibody
      • Poliovirus receptor related 2 (herpesvirus entry mediator B) antibody
      • Poliovirus receptor related 2 antibody
      • Poliovirus receptor related protein 2 antibody
      • Poliovirus receptor-related protein 2 antibody
      • PRR 2 antibody
      • PRR2 antibody
      • PVRL 2 antibody
      • PVRL2 antibody
      • PVRL2_HUMAN antibody
      • PVRR 2 antibody
      • PVRR2 antibody
      see all

    References

    This product has been referenced in:
    • Cocchi F  et al. Cell-to-cell spread of wild-type herpes simplex virus type 1, but not of syncytial strains, is mediated by the immunoglobulin-like receptors that mediate virion entry, nectin1 (PRR1/HveC/HIgR) and nectin2 (PRR2/HveB). J Virol 74:3909-17 (2000). Read more (PubMed: 10729168) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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