Overview

  • Product nameAnti-NEIL2 antibody
    See all NEIL2 primary antibodies
  • Description
    Mouse monoclonal to NEIL2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-333 of Human NEIL2

Properties

Applications

Our Abpromise guarantee covers the use of ab56577 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInvolved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
    • Tissue specificityDetected in testis, skeletal muscle, heart, brain, placenta, lung, pancreas, kidney and liver.
    • Sequence similaritiesBelongs to the FPG family.
      Contains 1 FPG-type zinc finger.
    • DomainThe zinc-finger domain is important for DNA binding.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • DNA glycosylase/AP lyase Neil2 antibody
      • DNA-(apurinic or apyrimidinic site) lyase Neil2 antibody
      • Endonuclease 8-like 2 antibody
      • Endonuclease VIII-like 2 antibody
      • NEH2 antibody
      • Nei endonuclease VIII like 2 (E. coli) antibody
      • Nei endonuclease VIII like 2 antibody
      • Nei homolog 2 antibody
      • Nei-like 2 antibody
      • Nei-like protein 2 antibody
      • NEI2 antibody
      • NEIL2 antibody
      • NEIL2_HUMAN antibody
      see all

    Anti-NEIL2 antibody images

    • Western blot against tagged recombinant protein immunogen using ab56577 NEIL2 antibody at 1ug/ml. Predicted band size of immunogen is 63 kDa

    References for Anti-NEIL2 antibody (ab56577)

    ab56577 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry and your interest in our products. The tag such as glutathione-S-transferase (GST) is often used for proteins for expression and purification applications. GST tag is a 26 kDa protein which is attached to the NEIL2 recom...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"