Anti-Neisseria gonorrhoeae antibody [12-316.4] (ab40998)

Overview

  • Product nameAnti-Neisseria gonorrhoeae antibody [12-316.4]
    See all Neisseria gonorrhoeae primary antibodies
  • Description
    Mouse monoclonal [12-316.4] to Neisseria gonorrhoeae
  • Specificityab40998 does not cross-react with N. meningitidis, N. cinerea, N.lactamica, N. sicca, B. catarrhalis, E.coli, P. mirabilis, Gardnerella vaginialis, Group B Strep. or Chlamydia trachomatis.
  • Tested applicationsSuitable for: ELISAmore details
  • Immunogen

    Pool of UV-inactivated Neisseria gonorrhoeae cells: Neisseria Reference Laboratory strains G-7, R-11and 7122 (W-I), 5766 and 8038 (WII), 8660 (W-III) .

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number12-316.4
  • IsotypeIgG2b
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab40998 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
  • Application notesELISA: 1/6400.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
    Dilute in PBS or medium which is identical to that used in the assay system.
  • Target

    • RelevanceNeisseria gonorrhoeae infections are acquired by sexual contact and usually affect the mucous membranes of the urethra in males and the endocervix and urethra in females, although the infection may disseminate to a variety of tissues. The pathogenic mechanism involves the attachment of the bacterium to nonciliated epithelial cells via pili (fimbriae) and the production of lipopolysaccharide endotoxin. Similarly, the lipopolysaccharide of Neisseria meningitidis is highly toxic, as it has an additional virulence factor in the form of its antiphagocytic capsule. Both pathogens produce IgA proteases which promote virulence. Many normal individuals may harbor Neisseria meningitidis in the upper respiratory tract, but Neisseria gonorrhoeae is never part of the normal flora and is only found after sexual contact with an infected person (or direct contact, in the case of infections in the newborn).
    • Alternative names
      • N gonorrhoeae antibody
      • N. gonorrhoeae antibody
      • N.gonorrhoeae antibody

    References for Anti-Neisseria gonorrhoeae antibody [12-316.4] (ab40998)

    ab40998 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"