Overview

  • Product name
    Anti-NEK6 antibody - C-terminal
    See all NEK6 primary antibodies
  • Description
    Rabbit polyclonal to NEK6 - C-terminal
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 250-280 of Mouse NEK6 (NP_001153103.1, NP_067619.1).

  • Positive control
    • Mouse liver tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab117245 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 36 kDa.

Target

  • Function
    Activated during M phase. Required for chromosome segregation at metaphase-anaphase transition and therefore for mitotic progression. Inhibition of activity results in apoptosis. Phosphorylates KIF11 to promote mitotic spindle formation.
  • Tissue specificity
    Ubiquitous, with highest expression in heart and skeletal muscle.
  • Sequence similarities
    Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Autophosphorylated.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Highly similar to cell cycle protein kinase CDC5/MSD2 antibody
    • NEK6 antibody
    • NEK6_HUMAN antibody
    • Never in mitosis A-related kinase 6 antibody
    • NIMA (Never In Mitosis Gene A) Related Kinase 6 antibody
    • NimA related protein kinase 6 antibody
    • NimA-related protein kinase 6 antibody
    • Protein kinase SID6 1512 antibody
    • Protein kinase SID6-1512 antibody
    • Putative serine threonine protein kinase antibody
    • Serine/threonine protein kinase Nek6 antibody
    • Serine/threonine-protein kinase Nek6 antibody
    • SID6 1512 antibody
    • SID61512 antibody
    see all

Images

  • Anti-NEK6 antibody - C-terminal (ab117245) at 1/100 dilution + Mouse liver tissue lysate at 35 µg

    Predicted band size : 36 kDa

References

ab117245 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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