Overview

  • Product nameAnti-NEK6 antibody [EPR5282]
    See all NEK6 primary antibodies
  • Description
    Rabbit monoclonal [EPR5282] to NEK6
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    A synthetic peptide corresponding to residues in Human NEK6

  • Positive control
    • HepG2, HeLa, 293T and HT-1080 cell lysates
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

Applications

Our Abpromise guarantee covers the use of ab109177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 36 kDa.
  • Application notesIs unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • FunctionActivated during M phase. Required for chromosome segregation at metaphase-anaphase transition and therefore for mitotic progression. Inhibition of activity results in apoptosis. Phosphorylates KIF11 to promote mitotic spindle formation.
    • Tissue specificityUbiquitous, with highest expression in heart and skeletal muscle.
    • Sequence similaritiesBelongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
      Contains 1 protein kinase domain.
    • Post-translational
      modifications
      Autophosphorylated.
    • Cellular localizationCytoplasm. Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • Highly similar to cell cycle protein kinase CDC5/MSD2 antibody
      • NEK6 antibody
      • NEK6_HUMAN antibody
      • Never in mitosis A-related kinase 6 antibody
      • NIMA (Never In Mitosis Gene A) Related Kinase 6 antibody
      • NimA related protein kinase 6 antibody
      • NimA-related protein kinase 6 antibody
      • Protein kinase SID6 1512 antibody
      • Protein kinase SID6-1512 antibody
      • Putative serine threonine protein kinase antibody
      • Serine/threonine protein kinase Nek6 antibody
      • Serine/threonine-protein kinase Nek6 antibody
      • SID6 1512 antibody
      • SID61512 antibody
      see all

    Anti-NEK6 antibody [EPR5282] images

    • All lanes : Anti-NEK6 antibody [EPR5282] (ab109177) at 1/1000 dilution

      Lane 1 : HepG2 lysate
      Lane 2 : HeLa cell lysate
      Lane 3 : 293T cell lysate
      Lane 4 : HT-1080 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 36 kDa

    References for Anti-NEK6 antibody [EPR5282] (ab109177)

    ab109177 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab109177.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"