Overview

  • Product name
  • Description
    Mouse polyclonal to NEK8
  • Host species
    Mouse
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Full length Human NEK8 (amino acids 1-692; NP_835464.1).

  • Positive control
    • NEK8 transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab169406 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 75 kDa.

Target

  • Function
    Required for renal tubular integrity.
  • Tissue specificity
    Highest expression in thyroid, adrenal gland and skin. Low levels in spleen, colon and uterus. Overexpressed in breast tumors, with highest expression in infiltrating ductal carcinomas and moderate levels in mucinous adenocarcinoma.
  • Sequence similarities
    Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
    Contains 1 protein kinase domain.
    Contains 5 RCC1 repeats.
  • Cellular localization
    Cytoplasm. Predominantly cytoplasmic.
  • Information by UniProt
  • Database links
  • Alternative names
    • JCK antibody
    • NEK 8 antibody
    • NEK12A antibody
    • NEK8 antibody
    • NEK8_HUMAN antibody
    • Nephrocystin 9 antibody
    • Never in mitosis A-related kinase 8 antibody
    • NIMA (never in mitosis gene a) related kinase 8 antibody
    • NIMA related kinase 8 antibody
    • NIMA-family kinase NEK8 antibody
    • NIMA-related kinase 12a antibody
    • Nima-related protein kinase 12a antibody
    • NimA-related protein kinase 8 antibody
    • NPHP9 antibody
    • Serine/threonine-protein kinase Nek8 antibody
    see all

Images

  • All lanes : Anti-NEK8 antibody (ab169406) at 1 µg/ml

    Lane 1 : NEK8 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 15 µl per lane.

    Predicted band size: 75 kDa

References

ab169406 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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