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Mouse polyclonal to Neprilysin-2
Recombinant full length protein corresponding to Human Neprilysin-2 aa 1-779.
MGKSEGPVGMVESAGRAGQKRPGFLEGGLLLLLLLVTAALVALGVLYADR RGKQLPRLASRLCFLQEERTFVKRKPRGIPEAQEVSEVCTTPGCVIAAAR ILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRDELEVIL KAVLENSTAKDRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWP VAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIY IDQPTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCL VQEDMVQVLELETQLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFN WTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLV WRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEVRWRECVGYVNSNMENA VGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWIDEESKKKAQEK AMSIREQIGHPDYILEETNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQR SLRKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQ ALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSEC MIYQYGNYSWDLADEQNVNGFNTLGENIADNGGVRQAYKAYLKWMAEGGK DQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHSPLKYRVLG SLQNLAAFADTFHCARGTPMHPKERCRVW
WB: Neprilysin-2 transfected 293T cell lysate.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 89 kDa.
Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond.
Predominantly expressed in testis. Weakly expressed in brain, kidney and heart.
Belongs to the peptidase M13 family.
Membrane. Secreted. A secreted form produced by proteollytic cleavage also exists.
Information by UniProt
Mel transforming oncogene like 1 antibody
Membrane metallo endopeptidase like 1 antibody
Membrane metallo endopeptidase like 2 antibody
has not yet been referenced specifically in any publications.
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