Overview

  • Product nameAnti-Nesprin3 antibody
    See all Nesprin3 primary antibodies
  • Description
    Rabbit polyclonal to Nesprin3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    KLH conjugated synthetic peptide corresponding to a region within C terminal amino acids 855-884 of Human Nesprin3 (NP_689805.3).

  • Positive control
    • Mouse spleen cell line lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab107616 is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab107616 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 112 kDa.

Target

  • FunctionComponent of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.
  • Sequence similaritiesBelongs to the nesprin family.
    Contains 1 KASH domain.
    Contains 2 spectrin repeats.
  • DomainThe KASH domain is involved in the binding to SUN1 and SUN2 through recognition of their SUN domains.
  • Cellular localizationNucleus outer membrane. Located at the rough reticulum endoplasmic (RER) in some cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • C14orf49 antibody
    • Chromosome 14 open reading frame 49 antibody
    • FLJ25605 antibody
    • MGC75267 antibody
    • Nesp3 antibody
    • Nesprin 3 antibody
    • Nesprin-3 antibody
    • NET53 antibody
    • Nuclear Envelope Spectrin Repeat Protein 3 antibody
    • Spectrin Repeat Containing, Nuclear Envelope Family Member 3 antibody
    • SYNE3 antibody
    • SYNE3_HUMAN antibody
    see all

Anti-Nesprin3 antibody images

  • Anti-Nesprin3 antibody (ab107616) at 1/100 dilution + Mouse spleen cell line lysate at 35 µg

    Predicted band size : 112 kDa

References for Anti-Nesprin3 antibody (ab107616)

ab107616 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"