Overview

  • Product nameAnti-NETO2 antibody
    See all NETO2 primary antibodies
  • Description
    Mouse monoclonal to NETO2
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Mouse, Rat, Chicken, Cow, Dog, Human
  • Immunogen

    Recombinant fragment: RRSSTASRCI HDHHCGSQAS SVKQSRTNLS SMELPFRNDF AQPQPMKTFN STFKKSSYTF KQGHECPEQA LEDRVMEEIP CEIYVRGRED SAQASISIDF, corresponding to amino acids 426-525 of Human NETO2 (NP_060562) with tag.

  • Positive control
    • Recombinant tagged human NETO2 fragment.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab77675 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 60 kDa.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionAccessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission.
    • Sequence similaritiesContains 2 CUB domains.
      Contains 1 LDL-receptor class A domain.
    • Post-translational
      modifications
      N-glycosylated.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Brain specific transmembrane protein antibody
      • Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 2 antibody
      • Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2 antibody
      • BTCL2 antibody
      • FLJ10430 antibody
      • FLJ14724 antibody
      • FLJ90456 antibody
      • NEOT2 antibody
      • NETO 2 antibody
      • Neto2 antibody
      • NETO2_HUMAN antibody
      • Neuropilin (NRP) and tolloid (TLL) like 2 antibody
      • Neuropilin and tolloid like protein 2 antibody
      • Neuropilin and tolloid-like protein 2 antibody
      see all

    Anti-NETO2 antibody images

    • Anti-NETO2 antibody (ab77675) at 1 µg/ml + Recombinant tagged human NETO2 fragment at 0.2 µg

      Secondary
      Goat anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

      Predicted band size : 60 kDa
      Observed band size : 35 kDa (why is the actual band size different from the predicted?)

    References for Anti-NETO2 antibody (ab77675)

    ab77675 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab77675.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"