Overview

  • Product nameAnti-Netrin 1 antibody
    See all Netrin 1 primary antibodies
  • Description
    Goat polyclonal to Netrin 1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Chicken, Xenopus laevis, Zebrafish
  • Immunogen

    Synthetic peptide:

    KFQQREKKGKCKKA

    , corresponding to C terminal amino acids 591-604 of Human Netrin 1 (NP_004813.2).

  • Positive control
    • Human brain (cerebellum), Mouse and Rat brain lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab106929 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 68 kDa).

Target

  • FunctionNetrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
  • Tissue specificityWidely expressed in normal adult tissues with highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas.
  • Sequence similaritiesContains 3 laminin EGF-like domains.
    Contains 1 laminin N-terminal domain.
    Contains 1 NTR domain.
  • Cellular localizationSecreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • epididymis tissue protein Li 131P antibody
    • NET1_HUMAN antibody
    • Netrin 1, mouse, homolog of antibody
    • Netrin 1-like antibody
    • Netrin-1 antibody
    • Netrin1 antibody
    • Ntn 1 antibody
    • NTN 1L antibody
    • NTN1 antibody
    • NTN1L antibody
    • Unc6 antibody
    see all

Anti-Netrin 1 antibody images

  • Anti-Netrin 1 antibody (ab106929) at 0.5 µg/ml + Rat brain lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 68 kDa
    Observed band size : ~70 kDa (why is the actual band size different from the predicted?)


    Exposure time : 1 hour

References for Anti-Netrin 1 antibody (ab106929)

ab106929 has not yet been referenced specifically in any publications.

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