Overview

  • Product name
  • Description
    Goat polyclonal to Netrin 1
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Cow, Dog
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to C terminal amino acids of Human Netrin 1.

  • Positive control
    • Human Intestine tissue; Rat, Mouse and Human Brain lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab122903 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 68 kDa).
IHC-P Use a concentration of 3.75 µg/ml.

Target

  • Function
    Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
  • Tissue specificity
    Widely expressed in normal adult tissues with highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas.
  • Sequence similarities
    Contains 3 laminin EGF-like domains.
    Contains 1 laminin N-terminal domain.
    Contains 1 NTR domain.
  • Cellular localization
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • epididymis tissue protein Li 131P antibody
    • NET1_HUMAN antibody
    • Netrin 1, mouse, homolog of antibody
    • Netrin 1-like antibody
    • Netrin-1 antibody
    • Netrin1 antibody
    • Ntn 1 antibody
    • NTN 1L antibody
    • NTN1 antibody
    • NTN1L antibody
    • Unc6 antibody
    see all

Anti-Netrin 1 antibody images

  • ab122903, at 3.75 µg/ml, staining Netrin 1 in Formalin-fixed, Paraffin-embedded Human Intestine tissue by Immunohistochemistry.
  • Anti-Netrin 1 antibody (ab122903) at 0.5 µg/ml + Rat Brain lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 68 kDa

References for Anti-Netrin 1 antibody (ab122903)

ab122903 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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