Overview

  • Product nameAnti-Neurabin 1 antibody
    See all Neurabin 1 primary antibodies
  • Description
    Rabbit polyclonal to Neurabin 1
  • Tested applicationsSuitable for: ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Rat, Human, Xenopus laevis
  • Immunogen

    Recombinant fragment corresponding to Rat Neurabin 1. Bacterially expressed coiled-coil domain of Rat neurabin I.

  • Positive control
    • WB: rat brain extract. ICC/IF: rat hippocampal cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab3483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.

Immunofluorescence staining of Neurabin 1 in cultured rat hippocampal cells results in diffuse cytoplasmic staining.

WB 1/1000. Detects a band of approximately 123 kDa (predicted molecular weight: 123 kDa).

Target

  • FunctionBinds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity.
  • Sequence similaritiesContains 1 PDZ (DHR) domain.
    Contains 1 SAM (sterile alpha motif) domain.
  • DomainInteracts with p70-S6K via its PDZ domain.
  • Cellular localizationCytoplasm > cytoskeleton. Cell junction > synapse > synaptosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ20068 antibody
    • KIAA1222 antibody
    • NEB1_HUMAN antibody
    • Neurabin I antibody
    • Neurabin-1 antibody
    • Neurabin-I antibody
    • Neurabin1 antibody
    • NeurabinI antibody
    • Neural tissue specific F actin binding protein I antibody
    • Neural tissue-specific F-actin-binding protein I antibody
    • NRB 1 antibody
    • NRB I antibody
    • NRB1 antibody
    • NRBI antibody
    • Ppp1r9a antibody
    • Protein phosphatase 1 regulatory (inhibitor) subunit 9A antibody
    • Protein phosphatase 1 regulatory subunit 9A antibody
    see all

Anti-Neurabin 1 antibody images

  • Immunolocalization of neurabin-1 in human brain tissue using ab3483.

References for Anti-Neurabin 1 antibody (ab3483)

This product has been referenced in:
  • Grgic I  et al. Discovery of new glomerular disease-relevant genes by translational profiling of podocytes in vivo. Kidney Int N/A:N/A (2014). Human . Read more (PubMed: 24940801) »

See 1 Publication for this product

Product Wall

Merci pour ce complément d'informations qui va nous permettre de chercher l'origine du problème rencontré avec le ab134081.

Comme convenu j'ai mis en place l'envoi d'une unité de ab3483 et d'une unité de lysa...

Read More
Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Xenopus laevis Cell (cultured retinal ganglion cell growth cone)
Specification cultured retinal ganglion cell growth cone
Fixative Paraformaldehyde
Permeabilization Yes - 0.1% triton x-100
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 21°C
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Submitted Dec 03 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"