• Product nameAnti-NEURL2 antibody
    See all NEURL2 primary antibodies
  • Description
    Rabbit polyclonal to NEURL2
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from an internal of human NEURL2.

  • Positive control
    • extracts from Jurkat cells, COLO cells and K562 cells; human heart tissue


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab74266 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 36 kDa (predicted molecular weight: 31 kDa).
ELISA 1/40000.
IHC-P 1/50 - 1/100.


  • FunctionPlays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma.
  • Tissue specificityExpressed specifically in skeletal and cardiac muscles.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesContains 1 NHR (neuralized homology repeat) domain.
    Contains 1 SOCS box domain.
  • DomainThe SOCS domain mediates the interaction with TCEB1 and TCEB2, while the NHR domain may be involved in ubiquitination substrate binding.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • NEUL2_HUMAN antibody
    • Neuralized like protein 2 antibody
    • Neuralized-like protein 2 antibody
    • NEURL2 antibody

Anti-NEURL2 antibody images

  • Immunohistochemistry analysis of paraffin-embedded human heart tissue using 1/50 ab74266. Left: untreated sample. Right: sample treated with immunising peptide.
  • All lanes : Anti-NEURL2 antibody (ab74266) at 1/500 dilution

    Lane 1 : extracts from Jurkat cells
    Lane 2 : extracts from COLO cells
    Lane 3 : extracts from K562 cells
    Lane 4 : extracts from Jurkat cells with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.

    Predicted band size : 31 kDa
    Observed band size : 36 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 26 kDa,48 kDa,65 kDa. We are unsure as to the identity of these extra bands.

References for Anti-NEURL2 antibody (ab74266)

ab74266 has not yet been referenced specifically in any publications.

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