• Product nameAnti-Neurobeachin antibody
    See all Neurobeachin primary antibodies
  • Description
    Goat polyclonal to Neurobeachin
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Cow, Dog, Pufferfish (Fugu), Zebrafish
  • Immunogen

    Synthetic peptide:


    , corresponding to C terminal amino acids 2934-2946 of Human Neurobeachin


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab58563 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesThis antibody gave a positive result in Peptide ELISA against the immunizing peptide. Antibody detection limit dilution 1/8000.

    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 300 kDa (predicted molecular weight: 327 kDa). Approx 300 kDa band observed in lysates of transfected HEK293 and endogenously in lysates of insulinoma cell line B-TC3.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionBinds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins.
    • Tissue specificityPredominant in many brain structures. Also expressed at medium levels in spleen, thymus, prostate, testis and ovary. Low level expression is seen in heart, kidney, pancreas, skeletal muscle and intestine.
    • Sequence similaritiesBelongs to the WD repeat neurobeachin family.
      Contains 1 BEACH domain.
      Contains 5 WD repeats.
    • DomainRII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.
    • Cellular localizationCytoplasm. Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • BCL8B antibody
      • FLJ10197 antibody
      • KIAA1544 antibody
      • Lysosomal trafficking regulator 2 antibody
      • Lysosomal-trafficking regulator 2 antibody
      • LYST2 antibody
      • NBEA antibody
      • NBEA_HUMAN antibody
      • Neurobeachin antibody
      • Protein BCL8B antibody
      • Protein neurobeachin antibody
      • RP11-270C18.1 antibody
      see all

    Anti-Neurobeachin antibody images

    • All lanes : Anti-Neurobeachin antibody (ab58563) at 1 µg/ml

      Lane 1 : Lysate prepared from non transfected HEK293 T cells
      Lane 2 : Lysate prepared from HEK293 T cells transfected with mouse Neurobeachin

      developed using the ECL technique

      Predicted band size : 327 kDa
      Observed band size : 300 kDa (why is the actual band size different from the predicted?)

    References for Anti-Neurobeachin antibody (ab58563)

    ab58563 has not yet been referenced specifically in any publications.

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