Overview

  • Product nameAnti-Neurogenin3 antibody [5A8]
    See all Neurogenin3 primary antibodies
  • Description
    Mouse monoclonal [5A8] to Neurogenin3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-214 of Human Neurogenin3, expressed in E.coli, (NM_020999).

  • Positive control
    • HEK293T cells transfected with pCMV6-ENTRY Neurogenin3 cDNA.
  • General notesDilute in PBS (pH7.3) before use.

Properties

Applications

Our Abpromise guarantee covers the use of ab117858 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Predicted molecular weight: 23 kDa.

Target

  • FunctionInvolved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types.
  • Involvement in diseaseDefects in NEUROG3 are the cause of diarrhea type 4 (DIAR4) [MIM:610370]. DIAR4 is a characterized by severe, life-threatening watery diarrhea associated with generalized malabsorption and a paucity of enteroendocrine cells.
  • Sequence similaritiesContains 1 basic helix-loop-helix (bHLH) domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • ATH4B antibody
    • Atoh5 antibody
    • bHLHa7 antibody
    • Class A basic helix-loop-helix protein 7 antibody
    • Math4B antibody
    • NEUROG3 antibody
    • Neurogenin-3 antibody
    • NGN-3 antibody
    • ngn3 antibody
    • NGN3_HUMAN antibody
    • OTTHUMP00000019730 antibody
    • Protein atonal homolog 5 antibody
    see all

Anti-Neurogenin3 antibody [5A8] images

  • All lanes : Anti-Neurogenin3 antibody [5A8] (ab117858) at 1/500 dilution

    Lane 1 : HEK293T cells transfected with pCMV6-ENTRY control
    Lane 2 : HEK293T cells transfected with pCMV6-ENTRY Neurogenin3 cDNA

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 23 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC200407)

References for Anti-Neurogenin3 antibody [5A8] (ab117858)

ab117858 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"