The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500. Predicted molecular weight: 23 kDa.
FunctionInvolved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types.
Involvement in diseaseDefects in NEUROG3 are the cause of diarrhea type 4 (DIAR4) [MIM:610370]. DIAR4 is a characterized by severe, life-threatening watery diarrhea associated with generalized malabsorption and a paucity of enteroendocrine cells.