Overview

  • Product nameAnti-Neuroketals antibody
  • Description
    Goat polyclonal to Neuroketals
  • Specificityab21214 targets neuroketal adducted proteins.
  • Tested applicationsSuitable for: ELISA, IHC-P, WBmore details
  • Immunogen

    Neuroketal conjugate.

Properties

Applications

Our Abpromise guarantee covers the use of ab21214 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
IHC-P
WB
  • Application notesELISA: 1/4000. IHC-P: 1/200. WB: 1/2000. Dilution optimised using Chromogenic detection. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceThe pathogenesis of many neurodegenerative diseases can be attributed to oxidative stress and protein aggregation. Patients of Alzheimer's disease show increased brain levels of neuroprostanes, compounds derived from the oxidation of docosahexaenoic acid. The Neuroketals, in such oxidative environments, are products of the neuroprostane pathway and are a species of highly reactive gamma-ketoaldehydes that rapidly adduct to lysine residues of proteins, causing cross-linking.
    • Alternative names
      • Gamma ketoaldehydes antibody

    References for Anti-Neuroketals antibody (ab21214)

    This product has been referenced in:
    • Serrano J  et al. Double-edged sword behaviour of gallic acid and its interaction with peroxidases in human microvascular endothelial cell culture (HMEC-1). Antioxidant and pro-oxidant effects. Acta Biochim Pol 57:193-8 (2010). WB . Read more (PubMed: 20532253) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"