• Product nameAnti-Neurokinin 1 Receptor antibody
    See all Neurokinin 1 Receptor primary antibodies
  • Description
    Rabbit polyclonal to Neurokinin 1 Receptor
  • SpecificityThis antibody is specific for human NK-1.
  • Tested applicationsSuitable for: Flow Cyt, WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Neurokinin 1 Receptor conjugated to Keyhole Limpet Haemocyanin (KLH).



  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPBS with 0.05% sodium azide
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notesFlow Cyt: 1/3000.
    ICC/IF: 1/5000 from (PubMed:17190739).
    WB: 1/1000. Detects a band of approximately 53 kDa (predicted molecular weight: 45 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionThis is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
    • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Neurokinin 1 antibody
      • NK 1 receptor antibody
      • NK 1R antibody
      • NK-1 receptor antibody
      • NK-1R antibody
      • NK1 receptor antibody
      • NK1R antibody
      • NK1R_HUMAN antibody
      • NKIR antibody
      • SPR antibody
      • Substance P receptor antibody
      • Substance-P receptor antibody
      • TAC 1R antibody
      • TAC1R antibody
      • Tachykinin 1 receptor (substance P receptor neurokinin 1 receptor) antibody
      • Tachykinin receptor 1 (substance P receptor neurokinin 1 receptor) antibody
      • Tachykinin receptor 1 antibody
      • TACR1 antibody
      see all

    References for Anti-Neurokinin 1 Receptor antibody (ab466)

    This product has been referenced in:
    • Amoruso A  et al. A novel activity for substance P: stimulation of peroxisome proliferator-activated receptor-gamma protein expression in human monocytes and macrophages. Br J Pharmacol 154:144-52 (2008). WB ; Human . Read more (PubMed: 18278062) »
    • El-Nour H  et al. Upregulation of the axonal growth and the expression of substance P and its NK1 receptor in human allergic contact dermatitis. Immunopharmacol Immunotoxicol 28:621-31 (2006). Read more (PubMed: 17190739) »

    See all 4 Publications for this product

    Product Wall

    Thank you for your enquiry. There are published reports stating that the substance P receptor/neurokinin-1 receptor (NK-1R) has two forms: a full-length receptor consisting of 407 aa and a truncated receptor consisting of 311 aa. Research has shown ...

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    Thank you for your enquiry. Unfortunately I cannot comment on whether the antibody recognises the intra- or extra-cellular domain as I am not an expert in the field. I can however tell you that the immunogen for this antibody is the at the N-termin...

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    Thank you for re-sending the information, I was able to open the attachments. Below is the FACS protocol which the researcher who tested it for Novus used. They also used lot C, so the vial that your customer received should be alright. I hope this is ...

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    This antibody has been used in rat tissue for western analysis with success(other applications are unknown)