Overview

  • Product name
    Anti-Neurokinin 1 Receptor antibody
    See all Neurokinin 1 Receptor primary antibodies
  • Description
    Rabbit polyclonal to Neurokinin 1 Receptor
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    A synthetic peptide derived from internal sequence of human Neurokinin 1 Receptor.

  • Positive control
    • Jurkat cell extracts.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab75516 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/5000.
WB 1/500 - 1/1000. Predicted molecular weight: 46 kDa.

Target

  • Function
    This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Neurokinin 1 antibody
    • NK 1 receptor antibody
    • NK 1R antibody
    • NK-1 receptor antibody
    • NK-1R antibody
    • NK1 receptor antibody
    • NK1R antibody
    • NK1R_HUMAN antibody
    • NKIR antibody
    • SPR antibody
    • Substance P receptor antibody
    • Substance-P receptor antibody
    • TAC 1R antibody
    • TAC1R antibody
    • Tachykinin 1 receptor (substance P receptor neurokinin 1 receptor) antibody
    • Tachykinin receptor 1 (substance P receptor neurokinin 1 receptor) antibody
    • Tachykinin receptor 1 antibody
    • TACR1 antibody
    see all

Anti-Neurokinin 1 Receptor antibody images

  • All lanes : Anti-Neurokinin 1 Receptor antibody (ab75516) at 1/500 dilution

    Lane 1 : Jurkat cell extract
    Lane 2 : Jurkat cell extract with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 46 kDa
    Observed band size : 48 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 19 kDa,60 kDa,85 kDa. We are unsure as to the identity of these extra bands.

References for Anti-Neurokinin 1 Receptor antibody (ab75516)

This product has been referenced in:
  • Wang H  et al. Increasing substance P levels in serum and synovial tissues from patients with developmental dysplasia of the hip (DDH). BMC Musculoskelet Disord 15:92 (2014). Read more (PubMed: 24642234) »
  • Chauhan VS  et al. Prophylactic and therapeutic targeting of the neurokinin-1 receptor limits neuroinflammation in a murine model of pneumococcal meningitis. J Immunol 186:7255-63 (2011). WB ; Mouse . Read more (PubMed: 21562162) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab75516.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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